I'm going to keep this short because everyone needs a good backup plan. For remote backups, I highly recommend CrashPlan. Their rates are reasonable, the software more or less easy to set up and use, and the value provided it absolutely worth the cost.

The CrashPlan is easily configurable, the interface is straightforward, the defaults are pretty good, but you can set your own limits on bandwidth and CPU (backup only on certain wifi networks). They encrypt the files on the user's side.

We use Crashplan to protect our managers and C-Level execs and it has been a great experience thus far. The key feature that sold us was the continuous backup (rather than relying on a schedule). My users are all highly mobile, and trying to protect their data with a fixed schedule would have been a fiasco. The app runs in the background, and its managed by our on premise crashplan server (which is a no-cost option). It's dead simple yet very effective.

We are currently using CashPlan across the company. It will solve all the problems with hard drive failures, virus and will make the process easier for users who are getting a computer replacement since we will just need to re-download the data that has been already backed up

We replaced another vendor's product with CrashPlan a couple of years ago, to overcome VPN dependencies, lack of frequent backup, and to get rid of all of our old in-house infrastructure. CrashPlan has been a stellar performer and our customers are extremely happy!